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The national database of the German Collaborative Arthritis Centres: II. Treatment of patients with rheumatoid arthritis

机译:德国合作性关节炎中心的国家数据库:II。类风湿关节炎的治疗

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摘要

OBJECTIVE—To describe current treatment of patients with rheumatoid arthritis (RA) in German rheumatology.
METHODS—Data from the German rheumatological database of 1998, comprising clinical and patient questionnaire data of 12 992 outpatients with RA seen at 24 collaborative arthritis centres in Germany, were analysed.
RESULTS—At the time of documentation, 88% of the patients with RA were undergoing disease modifying antirheumatic drug (DMARD) treatment. Methotrexate (MTX) was prescribed to 56% of the patients (61% with seropositive and 45% with seronegative RA). Combination treatment was used in 15%. MTX was the drug of first choice even in patients with up to one year's disease duration (49%), followed by antimalarial drugs (21%). Patients treated by non-rheumatologists within the previous year had received DMARD treatment in only 33% of the cases. In steroid treatment, low doses (⩽7.5 mg/day) were used by rheumatologists much more often (44%) than higher doses (12%). 16% of the patients had been inpatients during the previous year, with a median length of stay accumulated over the year of 21 days. Together with stays in inpatient rehabilitation, 22% of all patients had had some form of inpatient treatment. Comprehensive measures such as occupational therapy and patient education were prescribed to fewer than 12% of the patients, mostly during their hospital stay.
CONCLUSION—German rheumatologists do follow recent recommendations about early and effective treatment. However, there are still deficits in outpatient care with non-medicinal measures like occupational therapy and patient education, which may partly explain the high hospital admission rates.


机译:目的—在德国风湿病学中描述类风湿关节炎(RA)的当前治疗方法。方法-分析来自1998年德国风湿病学数据库的数据,该数据包括在德国24个协作性关节炎中心观察到的12例992例RA患者的临床和患者问卷调查数据。结果—在记录时,有88%的RA患者正在接受抗风湿药(DMARD)治疗。 56%的患者开了甲氨蝶呤(MTX)(血清阳性的患者占61%,血清阴性的RA患者占45%)。联合治疗的比例为15%。即使在疾病持续时间长达一年(49%)的患者中,MTX仍是首选药物,其次是抗疟药(21%)。在上一年中,由非风湿病学家治疗的患者仅接受了33%的病例的DMARD治疗。在类固醇治疗中,风湿科医生使用低剂量(⩽7.5毫克/天)的频率更高(12%)的频率更高(44%)。上一年中有16%的患者为住院患者,中位住院时间超过21天。加上住院康复治疗,所有患者中有22%接受了某种形式的住院治疗。不到12%的患者被规定采取职业治疗和患者教育等综合措施,主要是在住院期间。结论—德国风湿病医师确实遵循了有关早期和有效治疗的最新建议。但是,在门诊护理方面仍然存在诸如职业治疗和患者教育等非医学措施的不足,这可能部分解释了高住院率的原因。

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